Famed astrophysicist Neil deGrasse Tyson takes a tour of the Solar System and the known universe establishing the components of Earth's "address" within the Virgo Supercluster. He then shares the story of the person who championed an expansive understanding of Earth's place in the universe by presenting Renaissance Italian Giordano Bruno's vision of the universe as a limitless expanse of space and time. He then makes an exploration into the Cosmic Calendar, which dates back to the dawn of the Big Bang (similar to the presentation from episode 1 of the original series). The episode ends with deGrasse Tyson narrating how he met his mentor Carl Sagan, who hosted the first Cosmos series.

The Milky Way, our galaxy, is a magnificent sight in the night sky, but we know surprisingly little about it for certain. What is its shape? How many stars does it actually contain? What lies at its centre? The Gaia space telescope will answer these questions, being armed with the most advanced camera to leave our planet, and it will allow us to see our galaxy as we've never seen it before. The Sky at Night visits the factory in Chelmsford that made the astonishing sensor at the heart of the mission.

An exploration of Earth's cosmic neighbourhood. Looking beyond the borders of our solar system, what's nearby in our galaxy? How do the other objects in our local area influence life on Earth? And, how did Earth's place in the galaxy make it the perfect place for the development of advanced life? Now that the Voyagers have visited the outer planets of the solar system they are heading for new adventures in places astronomers call the Oort Cloud, the heliopause, heliosheath and eventually they may encounter double stars and exoplanets, some of which may pay a visit to the solar system one day or explode showering us with radiation. If the Voyagers live so long they will experience the local fluff, local bubble and other parts of the habitable zone of the galaxy.

Across the universe, galaxies are going dark, and scientists don't know why the stars are losing their shine. Something is slowly drawing the curtains closed on the universe. Our milky way is under threat. Astronomers race against time to uncover the truth behind how galaxies are born and how they die before all of the lights go out.

Questions are raised about the search for intelligent life beyond the Earth, with UFOs and other close encounters refuted in favor of communications through SETI and radio telescope such as the Arecibo Observatory. The probability of technically advanced civilizations existing elsewhere in the Milky Way is interpreted using the Drake equation and a future hypothetical Encyclopedia Galactica is discussed as a repository of information about other worlds in the galaxy. The Cosmos Update notes that there have been fewer sightings of UFOs and more stories of abductions, while mentioning the META scanning the skies for signals.

Our galaxy is one of hundreds of billions in the universe. View of universe through the Hubble telescope and go back almost all the way to the Big Bang.