The episode begins with Tyson describing how pattern recognition manifested in early civilization as using astronomy and astrology to predict the passing of the seasons, including how the passage of a comet was often taken as an omen. Tyson continues to explain that the origin of comets only became known in the 20th century due to the work of Jan Oort and his hypothesis of the Oort cloud. Tyson then continues to relate the collaboration between Edmond Halley and Isaac Newton in the last part of the 17th century in Cambridge. The collaboration would result in the publication of Philosophiæ Naturalis Principia Mathematica, the first major work to describe the laws of physics in mathematical terms, despite objections and claims of plagiarism from Robert Hooke and financial difficulties of the Royal Society of London. Tyson explains how this work challenged the prevailing notion that God had planned out the heavens, but would end up influencing many factors of modern life, including space flight. Tyson further describes Halley's contributions including determining Earth's distance to the sun, the motion of stars and predicting the orbit of then-unnamed Halley's Comet using Newton's laws. Tyson contrasts these scientific approaches to understanding the galaxy compared to what earlier civilizations had done, and considers this advancement as mankind's first steps into exploring the universe. The episode ends with an animation of the Milky Way and Andromeda galaxies' merging based on the principles of Newton's laws.

In the 80s the nature of the Latino Diaspora changes again. From Cuba a second wave of refugees to United States – the Mariel exodus – floods Miami . The same decade sees the sudden arrival of hundreds of thousands of Central Americans (Salvadorans, Guatemalans, and Nicaraguans) fleeing death squads and mass murders at home like activist, Carlos Vaquerano. By the early 1990s, a political debate over illegal immigration – has begun. Globalization, empowered by NAFTA, means that as U.S. manufacturers move south, Mexican workers head north in record numbers. A backlash ensues: tightened borders, anti-bilingualism, state laws to declare all illegal immigrants felons. But a sea change is underway: the coalescence of a new phenomenon called Latino American culture-as Latinos spread geographically and make their mark in music, sports, politics, business, and education.

The tour was designed by Willie Williams, who has worked on every U2 tour since 1982. Williams had been toying with ideas for 360-degree stadium staging for U2 for a number of years, and presented sketches of a four-legged design to the group near the end of their Vertigo Tour in 2006. The inspiration for the 'spaceship-on-four-legs' design, nicknamed 'the Claw', came from the landmark Theme Building at Los Angeles International Airport.

Do you make your own luck, or does luck make you? Some scientists believe luck is strictly a matter of statistics and probabilities…but others believe unseen forces are at work, and randomness is built into every particle of the universe. We’ll find luck, good and bad, in casinos, basketball courts, genetics labs and the subatomic world. How much does the genetic lottery rule your fate? Are lucky streaks and unfortunate accidents merely our own minds fooling us? It’s a scientific journey that will radically revise your understanding of the laws of nature and the workings of the human brain.

We move around in space, but we are stuck in a prison of time moving ever forwards. Einstein said, 'The distinction between past, present and future is only a stubbornly persistent illusion.' Is our experience of the ticking clock merely a trick of the mind? Could science ever make the clock move backwards? Experiments in quantum physics are showing that the future influences the present: what happens later limits the choices we think we have now. The laws of physics say visiting or talking to ourselves in the past is possible – but changing history once we get there is not.

Imagine a world where infinite copies of you are playing out every storyline of your life. It sounds like a plot stolen straight from Hollywood, but far from it. This is the multiverse. Until very recently the whole idea of the multiverse was dismissed as a fantasy, but now this strangest of ideas is at the cutting edge of science. And for a growing number of scientists, the multiverse is the only way we will ever truly make sense of the world we are in. Do multiple universes exist? And if so, which one are we actually in?" Imagine a world where dinosaurs still walk the earth. A world where the Germans won World War II and you are president of the United States. Imagine a world where the laws of physics no longer apply.