Who are you? Do you even know who you are? Are you your memories? Are you the choices you make? Are you you? Or are you someone else, but manipulated to be you? If you can lose track of your past and your memories can be altered or implanted, in the end, who are you really? Michael Stevens finds out as he explores what makes you you.

This episode looks at a group of black survivalists. British Buzzfeed correspondent Bim Adewunmi looks at an unusual group of doomsday preppers who don't fit the normal stereotype for that group. She interviews people of color who train themselves to prepare for disaster.

The films looks at the world of men's rights activists. Buzzfield reporter Scaachi Koul talks about her personal online encounters with the aggressive anti-feminist movement and talks to an expert who describes them as misogynistic. She talks to a female men's rights activist to find out what she has to say. She also looks at programs that try to help men without blaming women.

Sultan Mehmed II's siege of Constantinople enters its third week. Mehmed's artillery teams continue their relentless bombardment of Constantinople's walls. After his navy suffers a devastating defeat, Mehmed moves his ships overland to the Golden Horn in a daring, visionary feat. In the shadow of betrayal, Giustiniani attacks the Ottoman fleet.

Autistic minds provide windows into how we all think, feel, and behave. A complete brain science should be able to account for all kinds of minds and brains. As long as some minds remain a mystery, so too will all minds.
Michael Stevens travels to London to meet a blind, autistic savant with astonishing musical abilities, and volunteers to have his brain's function temporarily disrupted at UCLA's Neuromodulation Lab.

The fourth episode sees host Neil deGrasse Tyson exploring our eternal quest to end hunger and honoring Nikolai Ivanovic Vavilov, pioneer of modern plant breeding, who risked his life for a discovery that would change the history of science. Vavilov's story is marked by both the tenacity and creativity and is particularly tragic. Interwoven into Vavilov's somber narrative are warnings and treatments of science and its ethical implications, especially when science itself comes under attack from political forces.