From the Philippines to the US, Madagascar and Mexico, Professor Brian Cox explores the globe to reveal how a few fundamental laws of science gave birth to the most complex and unique feature of the universe - life. In the first episode, Brian journeys to the volcanic landscapes of South-East Asia, seeking to understand how life first began and how that spark has endured to this day.

The use of embryonic stem cells has ignited fierce debate across the spiritual and political spectrum. But what if we could create manmade stem cells - or find super cells in adults that could forever replace embryonic cells and remove the controversy? Today, we are on the brink of a new era - an age where we may be able to cure our bodies of any illness. Stephen Hawking has spent his life exploring the mysteries of the cosmos, now there is another universe that fascinates him - the one hidden inside our bodies - our own personal galaxies of cells." Hawking takes us on a fascinating journey exploring what these wondrous and baffling mechanisms are capable of. He is joined by the scientists who are on the front lines of discovery in this field including Dr. Doris Taylor who is customizing a donor's heart with the recipient's stem cells - her goal is to revolutionize heart transplants, Dr. Paul Lu and Dr. Mark Tuszynski may have created a breakthrough that could cure paralysis, and Dr. Vincent Giampapa who believes that stem cells can be used to stem the tide of aging and create a fountain of youth.

What triggered the incredible diversity of life on Earth, and how have complex life forms, including humans, evolved? Is there direction to evolution? And is human intelligence inevitable? This program focuses on evolution's 'great transformations' —among them the development of a standard four-limbed body plan, the journey from water to land, the return of marine mammals to the sea, and the emergence of humans. Driven by a combination of opportunism and a genetic 'toolkit', these astounding leaps forward define the arc of evolution. And they suggest that every living creature on earth today, and every species that has ever existed, is a variation on a grand genetic theme—a member of one, and only one, tree of life

The first episode looks at how birds first took to the skies in the wake of the insects. It begins in Mexico, where Sir Attenborough observes bats being outmanoeuvred by a red-tailed hawk. Pterosaurs were the birds' forerunners, some 150 million years after dragonflies developed the means of flight, but eventually went extinct together with the dinosaurs. Birds had by then already evolved from early forms like archaeopteryx, the first creature to possess feathers. Its ancestry can be traced through reptiles, and some current species, such as the flying lizard, possibly show paths this evolution may have taken." One of the biggest birds to have ever existed was the terror bird, which proliferated after dinosaurs vanished and stood up to 2.5 metres tall. By comparison, the ostrich, while not closely related, is the largest and heaviest living bird. It was probably the evasion of predators that drove most birds into the air, so their flightless cousins evolved because they had few enemies. Accordingly, such species are more likely to be found on islands, and Sir Attenborough visits New Zealand to observe its great variety, most especially the kiwi. Also depicted is the moa, another huge creature that is now gone. The takahē is extremely rare, and high in the mountains of New Zealand, Sir Attenborough discovers one from a population of only 40 pairs. Finally, another example on the brink of extinction is the kakapo, which at one point numbered only 61 individuals. A male is heard calling — an immensely amplified deep note that can be heard at great distances from its nest.

Professor Brian Cox seeks to understand the nature of time and its role in creating both the universe and ourselves. From an extraordinary calendar built into the landscape of Peru to the beaches of Costa Rica, Brian explores the cycles of time which define our experience of life on Earth. But even the most epic cycles of life can't begin to compare to the vast expanse of cosmic time. Ultimately, Brian discovers that time is not characterised by repetition but by irreversible change. The vast universe is subject to these same laws of change. As we look out to the cosmos, we can see the story of its evolution unfold, from the death of the first stars to the birth of the youngest. This journey from birth to death will ultimately lead to the destruction not just of our planet, but also the entire universe, and with it the end of time itself. Yet without this inevitable destruction, the universe would be without what is perhaps the greatest wonder of all; the brief moment in time in which life can exist.

A visit to arguably the most famous archipelago on Earth, the Galapagos. It's home to a myriad of bizarre and unique creatures, endemic to these islands - but how did they get here and what is the key to these extraordinary islands that allows them to thrive? The programme reveals that this key holds not just the secret to life here, but also to how Darwin was able to leave with the ideas that would revolutionise biology.