Heart disease is the number one cause of deaths worldwide, killing more than eight million people each year. Cardiac infarction, more commonly known as a heart attack, can happen without warning, killing heart muscle cells immediately. Even if the patient recovers, the damage to their heart may not.
But there are researchers frantically working to change that. Meet the people inventing the future of cardiac health, from new ways of imaging the body, to the possibility of 3D printing a functioning heart.

Reptiles and amphibians look like hang-overs from the past. But they overcome their shortcomings through amazing innovation. The pebble toad turns into a rubber ball to roll and bounce from its enemies. Extreme slow-motion shows how a Jesus Christ lizard runs on water, and how a chameleon fires an extendible tongue at its prey with unfailing accuracy. The camera dives with a Niuean sea snake, which must breed on land but avoids predators by swimming to an air bubble at the end of an underwater tunnel. In a TV first, Komodo dragons hunt a huge water-buffalo, biting it to inject venom, then waiting for weeks until it dies. Ten dragons strip the carcass to the bone in four hours.

Marine invertebrates are some of the most bizarre and beautiful animals on the planet, and thrive in the toughest parts of the oceans. Divers swim into a shoal of predatory Humboldt squid as they emerge from the ocean depths to hunt in packs. When cuttlefish gather to mate, their bodies flash in stroboscopic colours. Time-lapse photography reveals thousands of starfish gathering under the Arctic ice to devour a seal carcass. A giant octopus commits suicide for her young. A camera follows her into a cave which she walls up, then she protects her eggs until she starves. The greatest living structures on earth, coral reefs, are created by tiny animals in some of the world's most inhospitable waters.

Montezuma Dan Snow journeys to the ancient heart of Mexico in search of the lost civilisation of the Aztecs and their last and greatest ruler, Montezuma II (1502-1520). Montezuma inherited an empire of five million people, stretching from present-day Mexico to Nicaragua, from his uncle. His rule was marked by incessant warfare. Enemy states were growing more powerful and conquered tribes were becoming more rebellious. Within months of taking the throne in 1502, he went changed a man of good reason into a pitiless autocrat who declared himself a god, believing that fear and ruthlessness were the only ways to stop the empire falling apart. Yet it was at the hands of Cortes and the Spanish conquistadors that Montezuma met his downfall. But what was his relationship with Cortes, and why did such a ruthless leader submit to his captors with such relative ease? As Dan Snow visits the ruins and picks through current excavations, he pieces together the evidence of a gripping story: a divine tragedy of errors, the clash of civilisations, the end of a world - and a very human God.

Caravaggio's approach to painting was unconventional. He avoided the standard method of making copies of old sculptures and instead took the more direct approach of painting directly onto canvas without drawing first. He also used people from the street as his models. His dramatic painting was enhanced with intense and theatrical lighting. Caravaggio's fate was sealed when he killed a man in a duel in 1606. He fled to Naples where he attempted to paint his way out of trouble, he became a Knight, but was then imprisoned in Malta and then finally moved to Sicily. He was pardoned for murder in 1610, but died of a fever when attempting to return to Rome. For me the power of Caravaggio's art is the power of truth, not least the truth about ourselves. If we are ever to hope for redemption we have to start from the recognition that the Goliath competes with the David in all of us."

Journey through the long-vanished corners of prehistoric North America, beginning when man first entered the vast, unspoiled continent some 14,000 years ago, in this appealing BBC documentary. Witness ancient beasts, mammoths, mastodons, giant bears, and sabre-toothed cats, and see the legacies each has passed to their modern successors. Computer animation and digital effects bring to life mammoths, saber-toothed cats, giant ground sloths, short-faced bears, glyptodonts, and a plethora of smaller animals in a lush Ice Age mosaic.