Horizon uncovers the secret world of our dreams. In a series of cutting-edge experiments and personal stories, we go in search of the science behind this most enduring mystery and ask: where do dreams come from? Do they have meaning? And ultimately, why do we dream? What the film reveals is that much of what we thought we knew no longer stands true. Dreams are not simply wild imaginings but play a significant part in all our lives as they have an impact on our memories, the ability to learn, and our mental health. Most surprisingly, we find nightmares, too, are beneficial and may even explain the survival of our species.

We are in the grip of an allergy epidemic. 50 years ago one in 30 were affected, but in Britain today it is closer to one in three. Why this should be is one of modern medicine's greatest puzzles. In search of answers, Horizon travels round the globe, from the remotest inhabited island to the polluted centres of California and the UK. We meet sufferers and the scientists who have dedicated their lives trying to answer the mystery of why we are becoming allergic to our world.

Professor Marcus du Sautoy goes in search of answers to one of science's greatest mysteries: how do we know who we are? While the thoughts that make us feel as though we know ourselves are easy to experience, they are notoriously difficult to explain. He has his mind scrambled by a cutting-edge experiment in anaesthesia. After, Marcus is given an out-of-body experience in a bid to locate his true self.

Dr Alice Roberts asks one of the great questions about our species: are we still evolving? There's no doubt that we're a product of millions of years of evolution. But thanks to modern technology and medicine, did we escape Darwin's law of the survival of the fittest? Alice follows a trail of clues from ancient human bones to studies of remarkable people living in the most inhospitable parts of the planet and the frontiers of genetic research, to discover if we are still evolving - and where we might be heading.

The drug policies have remained unchanged over the last 40 years so should they be reformed in the light of new research? Recent research has analysed the link between the harmful effects of drugs relative to their current classification by law with some startling conclusions. Perhaps most startling of all is that alcohol, solvents and tobacco (all unclassified drugs) are rated more dangerous than ecstasy, 4-MTA and LSD (all class A drugs).

Richard Dawkins examines the growing suspicion the public has for science-based medicine, despite its track record of successes like the germ theory of disease, vaccines, antibiotics and increased lifespan. He notes a fifth of British children are currently not immunised against measles, mumps and rubella, attributing it to fears arising from a highly controversial report linking the vaccine with autism. Dawkins criticizes the growing field of alternative medicine which does not pass the same objective and statistical rigour as scientifically derived treatments using controlled double-blind studies. Without verifiable evidence, alternative therapies must rely on biased anecdotes and word of mouth to perpetuate. Dawkins observes these treatments have fanciful rationales and rituals behind them, with many alternative treatments employing pseudoscientific jargon such as "energy", "vibration" or "quantum theory" to give themselves greater credence to patients.