They are the most powerful objects in the universe. Nothing, not even light, can escape the gravitational pull of a black hole. Astronomers now think there are billions of them out in the cosmos, swallowing up planets, even entire stars in violent feeding frenzies. New theoretical research into the twisted reality of black holes suggests that three-dimensional space could be an illusion. That reality actually takes place on a two-dimensional hologram at the edge of the universe.

Einstein's world-shaking Theory of Relativity says that time travel is perfectly possible -- if you're going forward in time. Finding a way to travel backwards requires breaking the speed of light, which so far seems impossible. But now, strange-but-true phenomena such as quantum nonlocality (where particles instantly teleport across vast distances) may give us a way to make the dream of traveling back and forth through time a reality. Step into a time machine and rewrite history, bring loved ones back to life, control our destinies. But if succeed, what are the consequences of such freedom? Will we get trapped in a plethora of paradoxes and multiple universes that will destroy the fabric of the universe?

Everywhere we look in the most hospitable of environments and in the most extreme we find life. On Earth, life exists everywhere we look. Yet we have only ever found life on our planet. How did the stuff of stars come together to create life as we know it? What do we really mean by 'life'? And will unlocking this mystery help us find life elsewhere?

Aliens almost certainly do exist. So why haven't we yet met E.T.? It turns out we're only just developing instruments powerful enough to scan for them, and science sophisticated enough to know where to look. As a result, race is on to find the first intelligent aliens. But what would they look like, and how would they interact with us if we met? The answers may come to us sooner than we imagine, for one leading astronomer believes she may already have heard a hint of their first efforts to communicate

What is the universe made of? If you answered stars, planets, gas and dust, you'd be dead wrong. Thirty years ago, scientists first realized that some unknown dark substance was affecting the way galaxies moved. Today, they think there must be five times our understanding of the universe and the nature of reality itself has drastically changed over the last 100 years - and it's on the verge of another seismic shift. In a 17-mile-long tunnel buried 570 feet beneath the Franco-Swiss border, the world's largest and most powerful atom smasher, the Large Hadron Collider, is powering up. Its goal is nothing less than recreating the first instants of creation, when the universe was unimaginably hot and long-extinct forms of matter sizzled and cooled into stars, planets, and ultimately, us. These incredibly small and exotic particles hold the keys to the greatest mysteries of the universe. What we find could validate our long-held theories about how the world works and what we are made of -- or, all of our notions about the essence of what is real will fall apart.

Everyone from the most simple-minded to the deepest thinking has pondered a question that strikes at the core of our existence: Is there life after death? What happens to the soul after we die? People who have had near-death experiences claim to have visited the other side before getting yanked back into consciousness. Now, some of the brightest minds in science are trying to understand how life can persist beyond the physical and what will it look like. It might be a quantum state based on the fundamental laws of the universe. Ultimately, it is a journey that struggles to decode the most complicated instrument in the universe: the human brain.