Beginning with the origins of the universe in the Big Bang, Sagan describes the formation of different types of galaxies and anomalies such as galactic collisions and quasars. The episodes moves further into ideas about the structure of the Universe, such as different dimensions (in the imaginary Flatland and four-dimensional hypercubes), an infinite vs. a finite universe, and the idea of an oscillating Universe (similar to that in Hindu cosmology). The search into other ideas such as dark matter and the multiverse is shown, using tools such as the Very Large Array in New Mexico. Cosmos Update shows new information about the odd, irregular surfaces of galaxies and the Milky Way perhaps being a barred spiral galaxy

This episode explores the wave theory of light as studied by mankind, noting that light has played an important role in scientific progress, with such early experiments from over 2000 years ago involving the camera obscura by the Chinese philosopher Mozi. Tyson describes the work of the 11th century Arabic scientist Ibn al-Haytham, considered to be one of the first to postulate on the nature of light and optics leading to the concept of the telescope, as well as one of the first researchers to use the scientific method. Tyson proceeds to discuss the nature of light as discovered by mankind. Work by Isaac Newton using diffraction through prisms demonstrated that light was composed of the visible spectrum, while findings of William Herschel in the 19th century showed that light also consisted of infrared rays. Joseph von Fraunhofer would later come to discover that by magnifying the spectrum of visible light, gaps in the spectrum would be observed. These Fraunhofer lines would later be determined to be caused by the absorption of light by electrons in moving between atomic orbitals when it passed through atoms, with each atom having a characteristic signature due to the quantum nature of these orbitals. This since has led to the core of astronomical spectroscopy, allowing astronomers to make observations about the composition of stars, planets, and other stellar features through the spectral lines, as well as observing the motion and expansion of the universe, and the existence of dark matter.

Tyson describes the discovery of cosmic rays by Victor Hess through high-altitude balloon trips. Swiss Astronomer Fritz Zwicky, in studying supernovae, postulated that these cosmic rays originated from these events instead of electromagnetic radiation. Also tells how Vera Rubin observed that the rotation of stars at the edges of observable galaxies did not follow expected rotational behavior leading to consider the existence of dark matter. This further led to the discovery of dark energy to account for the increasing rate of expansion of the universe. Tyson then describes the interstellar travel of the two Voyager probes. Tyson tells the Carl Sagan's role in the Voyager program, including creating the Voyager Golden Record to encapsulate humanity and Earth's position in the universe. Tyson concludes the series by emphasizing Sagan's message on the human condition in the vastness of the cosmos, and to encourage viewers to continue to explore and discover what else the universe has to offer.

When we look up into the sky it appears we live in a universe that is filled with light. But scientists are now certain there is far more matter in the dark portions of our universe that we can’t see or touch. There’s something hiding in the shadows. Cosmologists agree that 'dark matter' has helped shape our Universe, but now they need to figure out what dark matter is. What’s going on in this hidden world? Could it have formed its own dark stars, planets, and even life forms? Could this Shadow Universe threaten our world of light?

Astronomers make an extraordinary discovery out in deep space when they uncover a cosmic mega-structure that's one billion light-years long. Now, investigators race to decode the hidden forces that shape the most massive and mysterious structure known in the Universe.
We dive into this space great wall's fiery birth and hunt for the weird cosmic glue that holds it together to reveal how this megastructure rewrites our understanding of the universe on an epic scale.

Our world, our solar system, our universe, none of it would exist without a ghostly particle called the neutrino. They are our early warning system whenever there's trouble in the universe. Neutrinos trigger star-killing explosions, supernovas. Neutrinos can answer so many questions, from why do we exist to how was the universe created. Neutrinos can be the very reason that we exist at all. The more we understand these elusive particles, the more we can gain insight into how the universe works.