The Taiga forest, on the edge of the Arctic, is a silent world of stunted conifers. The trees may be small but filming from the air reveals its true scale. A third of all trees on Earth grow here and during the short summer they produce enough oxygen to change the atmosphere. In California General Sherman, a giant sequoia, is the largest living thing on the planet, ten times the size of a blue whale. The oldest organisms alive are bristlecone pines. At more than 4,000 years old they pre-date the pyramids. But the baobab forests of Madagascar are perhaps the strangest of all.

They are the most powerful objects in the universe. Nothing, not even light, can escape the gravitational pull of a black hole. Astronomers now think there are billions of them out in the cosmos, swallowing up planets, even entire stars in violent feeding frenzies. New theoretical research into the twisted reality of black holes suggests that three-dimensional space could be an illusion. That reality actually takes place on a two-dimensional hologram at the edge of the universe.

They soar through the heavens, fly through the oceans and glide along land. But these are not creatures found on a wildlife safari. These are life forms from another planet. Armed with scientific fact and a little imagination, experts come together to take you on an unprecedented journey to the edges of our imagination.

Beginning with the origins of the universe in the Big Bang, Sagan describes the formation of different types of galaxies and anomalies such as galactic collisions and quasars. The episodes moves further into ideas about the structure of the Universe, such as different dimensions (in the imaginary Flatland and four-dimensional hypercubes), an infinite vs. a finite universe, and the idea of an oscillating Universe (similar to that in Hindu cosmology). The search into other ideas such as dark matter and the multiverse is shown, using tools such as the Very Large Array in New Mexico. Cosmos Update shows new information about the odd, irregular surfaces of galaxies and the Milky Way perhaps being a barred spiral galaxy

Tyson describes the discovery of cosmic rays by Victor Hess through high-altitude balloon trips. Swiss Astronomer Fritz Zwicky, in studying supernovae, postulated that these cosmic rays originated from these events instead of electromagnetic radiation. Also tells how Vera Rubin observed that the rotation of stars at the edges of observable galaxies did not follow expected rotational behavior leading to consider the existence of dark matter. This further led to the discovery of dark energy to account for the increasing rate of expansion of the universe. Tyson then describes the interstellar travel of the two Voyager probes. Tyson tells the Carl Sagan's role in the Voyager program, including creating the Voyager Golden Record to encapsulate humanity and Earth's position in the universe. Tyson concludes the series by emphasizing Sagan's message on the human condition in the vastness of the cosmos, and to encourage viewers to continue to explore and discover what else the universe has to offer.

The tour was designed by Willie Williams, who has worked on every U2 tour since 1982. Williams had been toying with ideas for 360-degree stadium staging for U2 for a number of years, and presented sketches of a four-legged design to the group near the end of their Vertigo Tour in 2006. The inspiration for the 'spaceship-on-four-legs' design, nicknamed 'the Claw', came from the landmark Theme Building at Los Angeles International Airport.