Heart disease is the number one cause of deaths worldwide, killing more than eight million people each year. Cardiac infarction, more commonly known as a heart attack, can happen without warning, killing heart muscle cells immediately. Even if the patient recovers, the damage to their heart may not.
But there are researchers frantically working to change that. Meet the people inventing the future of cardiac health, from new ways of imaging the body, to the possibility of 3D printing a functioning heart.

Montezuma Dan Snow journeys to the ancient heart of Mexico in search of the lost civilisation of the Aztecs and their last and greatest ruler, Montezuma II (1502-1520). Montezuma inherited an empire of five million people, stretching from present-day Mexico to Nicaragua, from his uncle. His rule was marked by incessant warfare. Enemy states were growing more powerful and conquered tribes were becoming more rebellious. Within months of taking the throne in 1502, he went changed a man of good reason into a pitiless autocrat who declared himself a god, believing that fear and ruthlessness were the only ways to stop the empire falling apart. Yet it was at the hands of Cortes and the Spanish conquistadors that Montezuma met his downfall. But what was his relationship with Cortes, and why did such a ruthless leader submit to his captors with such relative ease? As Dan Snow visits the ruins and picks through current excavations, he pieces together the evidence of a gripping story: a divine tragedy of errors, the clash of civilisations, the end of a world - and a very human God.

Every cosmologist and astronomer agrees: our Universe is 13.7 billion years old. Using cutting-edge technology, scientists are now able to take a snapshot of the Universe a mere heartbeat after its birth. Armed with hypersensitive satellites, astronomers look back in time to the very moment of creation, when all the matter in the Universe exploded into existence. It is here that we uncover an unsolved mystery as old as time itself -- if the Universe was born, where did it come from? Meet the leading scientists who have now discovered what they believe to be the origin of our Universe, and a window into the time before time.

Andrew Graham-Dixon reveals how the Medici family transformed Florence through sculpture, painting and architecture and created a world where masterpieces fetch millions today. Without the money and patronage of the Medici we might never have heard of artists such as Donatello, Michelangelo or Botticelli, and Graham-Dixon examines how a family of shadowy, corrupt businessmen, driven by greed and ambition, became the financial engine behind the Italian Renaissance.

It has taken 4.6 billion years for the Earth to evolve from a barren rock into the world we know today. Explore the forces beyond our planet that have determined Earth’s destiny -- forces of destruction and regeneration in the solar system that created the planet and still protect it. And now the remarkable planet is facing a new challenge: humankind. The question is, how will it survive?

The Milky Way, our galaxy, is a magnificent sight in the night sky, but we know surprisingly little about it for certain. What is its shape? How many stars does it actually contain? What lies at its centre? The Gaia space telescope will answer these questions, being armed with the most advanced camera to leave our planet, and it will allow us to see our galaxy as we've never seen it before. The Sky at Night visits the factory in Chelmsford that made the astonishing sensor at the heart of the mission.