Rembrandt's success in his early years was as a portrait painter to the rich denizens of Amsterdam at a time when the city was being transformed from a small nondescript port into the economic capital of the world. His historical and religious paintings also gave him wide acclaim. Despite being known as a portrait painter Rembrandt used his talent to push the boundaries of painting. This direction made him unpopular in the later years of his career as he shifted from being the talk of the town to becoming adrift in the Amsterdam art scene and criticised by his peers.

One of Britain's most celebrated artists, Turner showed exceptional artistic talent from an early age and entered the Royal Academy aged fourteen. His English landscapes made his name but there was a darker side to his paintings that was difficult for the critics to swallow, both in the increasingly informal use of paint and the subject matter that was critical of the romanticised vision of Britain in the late nineteenth century.

Guernica (1937) was created during Picasso's Surrealist period and captures the horror of the bombing of the Basque town of Guernica during the Spanish Civil War. By the end of World War II, Picasso had become an internationally known artist and celebrity.

Rothko is known for his abstract expressionism paintings, but he moved through more traditional styles in his early career, including Surrealist paintings in the 1940s. In 1947 he embarked on the first of his large abstract 'colour-field' paintings, formalising their structure further in the 1950s. Rothko had huge success with largescale solo shows, but committed suicide in 1970.

Dr Alice Roberts looks at our ancestors' seemingly impossible journey to Australia. Miraculously preserved footprints and very old human fossils buried in the outback suggest a mystery: that humans reached Australia almost before anywhere else. How could they have travelled so far from Africa, crossing the open sea on the way, and do it thousands of years before they made it to Europe? The evidence trail is faint and difficult to pick up, but Alice takes on the challenge. In India, new discoveries among the debris of a super volcano hint that our species started the journey much earlier than previously thought, while in Malaysia, genetics points to an ancient trail still detectable in the DNA of tribes today. Alice travels deep into the Asian rainforests in search of the first cavemen of Borneo and tests out a Stone Age raft to see whether sea travel would have been possible thousands of years ago, before coming to a powerful conclusion.

Michael Wood’s epic series moves on to the revolutionary years after 500BC - the Age of the Buddha. Travelling by rail to the ancient cities of the Ganges plain, by army convoy through Northern Iraq, and on down the Khyber Pass, he shows how Alexander the Great’s invasion of India inspired her first empire.