In Bhutan, Palin finds himself back in the land of yaks for a last look at the high Himalaya. Trekking to Chomolhari base camp he meets a nomad with a penchant for yak songs before heading down to Paro to witness the Buddhist festival or Tsechu. In a bar in Thimphu, he discusses reincarnation and the pursuit of happiness with Benji and Khendum, two of the king's cousins, and en route to Bangladesh is taken by Benji to see the rare black-neck cranes. On his journey south through Bangladesh, Michael visits the ship-breaking beaches of Chittagong and grid-locked Dhaka. He meets a man who made a fortune in Birmingham in the poultry business, and a woman who lends money only to women. On a 1920s paddle steamer he is serenaded with the words of Bengal's Shakespeare, and he completes his epic Himalayan journey aboard a fishing boat that carries him out into the Bay of Bengal and a westering sun.

Through the mountains and jungles of Colombia, Cooper goes in search of the truth behind one of the greatest stories ever told - the legend of El Dorado. His journey takes him from Bogota to the Caribbean coast, through territories once dominated by two cultures, the Muisca and the Tairona, who flourished for centuries before the arrival of the Spanish in the 16th century. Cooper reveals forgotten peoples who valued gold in a way the Western world still struggles to understand, travelling to an astonishing lost city and meeting the last survivors of an ancient civilisation.

Tyson describes the discovery of cosmic rays by Victor Hess through high-altitude balloon trips. Swiss Astronomer Fritz Zwicky, in studying supernovae, postulated that these cosmic rays originated from these events instead of electromagnetic radiation. Also tells how Vera Rubin observed that the rotation of stars at the edges of observable galaxies did not follow expected rotational behavior leading to consider the existence of dark matter. This further led to the discovery of dark energy to account for the increasing rate of expansion of the universe. Tyson then describes the interstellar travel of the two Voyager probes. Tyson tells the Carl Sagan's role in the Voyager program, including creating the Voyager Golden Record to encapsulate humanity and Earth's position in the universe. Tyson concludes the series by emphasizing Sagan's message on the human condition in the vastness of the cosmos, and to encourage viewers to continue to explore and discover what else the universe has to offer.

Series concludes with the focus shifting to the United States in the post-war years of the 1950s and beyond. Beginning with arguably the most notorious work of 20th century classical music, John Cage's 'silent' composition 4'33", it looks at how a series of maverick Americans re-invented the sound of classical music into a more simple form, bringing back harmonies and rhythms that made it increasingly popular with audiences across the world. It also examines how this music found its way into a spiritual realm, with the strain of pared-down religious composition that came to be known as 'holy minimalism'. From the Maverick concert hall in Woodstock, New York to an Orthodox cathedral in Estonia to a car park in Peckham, south London, the story is told by a stellar line-up of contributors including Philip Glass, Steve Reich, John Adams, Arvo Pärt and John Tavener.

For the animals in the polar regions, autumn means dramatic battles and epic journeys. Time is running out - the Arctic Ocean is freezing over and the sea ice is advancing at 2.5 miles per day around Antarctica. Polar bears gather in large numbers on the Arctic coast as they wait for the return of the ice. Soon, tempers fray and violent sparring contests break out. Meanwhile 2,000 beluga whales head for one special estuary, a gigantic 'whale spa' where they will thrash their snow-white bodies against the gravel and exfoliate. Inland, the tundra undergoes a dramatic transformation from green to fiery red. Here, musk ox males slam head-first into each other with the force of a 30mph car crash as they struggle to defend their harems. Frisky young caribou males play a game of 'grandma's footsteps' as they try to steal the boss's female. Down in Antarctica, Adelie penguin chicks huddle together in creches. When a parent returns from fishing, it leads its twins on a comical steeplechase - sadly there's only enough for one, so the winner gets the meal. Two months later and the chicks are fully feathered apart from downy Mohican hairdos - they're ready to take their first swim - reluctantly though, as it seems penguins are not born with a love of water! And with good reason - a leopard seal explodes from the sea and pulls one from an ice floe, a hunting manoeuvre that has never been filmed before. As winter approaches and everyone has left, the giant emperor penguin arrives and makes an epic trek inland to breed. The mothers soon return to the sea leaving the fathers to hold the eggs and endure the coldest winter on earth.

In late Cretaceous Canada, in what will be known as Dinosaur Provincial Park, a Daspletosaurus stalks a Chasmosaurus in a forest, but loses the element of surprise and is forced to retreat. The Chasmosaurus comes across a younger Daspletosaurus, before being ambushed by a group of the tyrannosaurids. The episode then cuts to the high Arctic, where Edmontosaurus are hunted by a large species of Troodon. The theropods attack at night, separating a juvenile from the herd and severely wounding it, only to be driven away by an adult. In the morning, they return to eat the carcass of the juvenile, which died during the night. The episode returns to the Daspletosaurus, who chase and bring down the Chasmosaurus. The larger adults bully the youngsters off the carcass, forcing them to wait until they have finished. The episode then cuts to Madagascar, where a mother Majungasaurus (an Abelisaurid) and her two offspring chase a group of Rahonavis off a carcass. However, they are temporarily driven off themselves by a male Majungasaurus. But, after he steals some food from one of the young, the female attacks him, before she and her young cannibalise his body. The episode returns once again to North America, where the Daspletosaurus are waiting for the annual migration of Centrosaurus. They attack during a rainstorm, killing some of the ceratopsians. The Centrosaurus make it to a flooded river and begin to swim across, and although many make it to the other side, some are caught by giant crocodilians or are severely wounded by floating debris and thus drown, or drown for unseen reasons. In the morning, the carcasses attract scavengers, including the Daspletosaurus. A montage is then shown of Daspletosaurus and Majungasaurus, the narrator saying that together, the tyrannosaurids and abelisaurids were the last of the killer dinosaurs.