For Charley Boorman and Ewan McGregor, their journey in the smooth Ecuadorian roads would most definitely have come as a relief after some rough terrain riding. Next up, they stop by one of the factories that make the famed Panama hats. One of the local producers explains that making them by hand takes roughly up to a month. At the other end, the crew on the Rivians make a dash for Central America where they have to ferry their trucks across as the Darién Gap blocks their path. On their way, they make a quick pitstop at one of the cacao factories to know more about cocoa production, one of the economic drivers of the country.

Ewan and Charley swap their e-Harley Davidsons for plane first and follow it up with a journey by ship to Panama. McGregor's bike needs some repairs and will be fixed by the time they reach Costa Rica. The ship they travel in with the bikes looks like a beaten-down vessel that raises genuine concerns about making the journey in one piece. The boat crew looks sharp and proactive while trying to make the show crew's journey as comfortable and safe as possible. The episode also introduces Nuqui, one of the wettest regions in the world where the ship quickly makes a pitstop to fuel up on essential supplies.

NASA is on a mission to send humans to Mars within just 15 years, but to reach this next frontier of space exploration, experts must discover new technology and cutting-edge science that protects astronauts from the Red Planet's deadliest killers.