Heart disease is the number one cause of deaths worldwide, killing more than eight million people each year. Cardiac infarction, more commonly known as a heart attack, can happen without warning, killing heart muscle cells immediately. Even if the patient recovers, the damage to their heart may not.
But there are researchers frantically working to change that. Meet the people inventing the future of cardiac health, from new ways of imaging the body, to the possibility of 3D printing a functioning heart.

Marine invertebrates are some of the most bizarre and beautiful animals on the planet, and thrive in the toughest parts of the oceans. Divers swim into a shoal of predatory Humboldt squid as they emerge from the ocean depths to hunt in packs. When cuttlefish gather to mate, their bodies flash in stroboscopic colours. Time-lapse photography reveals thousands of starfish gathering under the Arctic ice to devour a seal carcass. A giant octopus commits suicide for her young. A camera follows her into a cave which she walls up, then she protects her eggs until she starves. The greatest living structures on earth, coral reefs, are created by tiny animals in some of the world's most inhospitable waters.

Montezuma Dan Snow journeys to the ancient heart of Mexico in search of the lost civilisation of the Aztecs and their last and greatest ruler, Montezuma II (1502-1520). Montezuma inherited an empire of five million people, stretching from present-day Mexico to Nicaragua, from his uncle. His rule was marked by incessant warfare. Enemy states were growing more powerful and conquered tribes were becoming more rebellious. Within months of taking the throne in 1502, he went changed a man of good reason into a pitiless autocrat who declared himself a god, believing that fear and ruthlessness were the only ways to stop the empire falling apart. Yet it was at the hands of Cortes and the Spanish conquistadors that Montezuma met his downfall. But what was his relationship with Cortes, and why did such a ruthless leader submit to his captors with such relative ease? As Dan Snow visits the ruins and picks through current excavations, he pieces together the evidence of a gripping story: a divine tragedy of errors, the clash of civilisations, the end of a world - and a very human God.

Caravaggio's approach to painting was unconventional. He avoided the standard method of making copies of old sculptures and instead took the more direct approach of painting directly onto canvas without drawing first. He also used people from the street as his models. His dramatic painting was enhanced with intense and theatrical lighting. Caravaggio's fate was sealed when he killed a man in a duel in 1606. He fled to Naples where he attempted to paint his way out of trouble, he became a Knight, but was then imprisoned in Malta and then finally moved to Sicily. He was pardoned for murder in 1610, but died of a fever when attempting to return to Rome. For me the power of Caravaggio's art is the power of truth, not least the truth about ourselves. If we are ever to hope for redemption we have to start from the recognition that the Goliath competes with the David in all of us."

Did you know that 1% of the white noise you see on old televisions is background radiation from The Big Bang? That the gold on a wedding ring comes from a star that exploded 5 billion years ago? And, that we're connected to the salt water of the first oceans through the water in our bodies? Our human story is actually 14 billion years old and the clues are all around us. This CGI-driven special will tell the history of our world in two hours, an ambitious story that will give surprising connections to our daily lives. From the formation of the earth and the emergence of life, to the advance of man and the growth of civilization, it’s a rapid-fire view of our unforgettable story.

Fifty years ago there were close to half-a-million lions in Africa. Today there are around 20,000. To make matters worse, lions, unlike elephants, which are far more numerous, have virtually no protection under government mandate or through international accords. This is the jumping-off point for a disturbing, well-researched and beautifully made cri de coeur from husband and wife team Dereck and Beverly Joubert, award-winning filmmakers from Botswana who have been Explorers-in-Residence at National Geographic for more than four years. Pointing to poaching as a primary threat while noting the lion's pride of place on the list for eco-tourists-an industry that brings in 200 billion dollars per year worldwide-the Jouberts build a solid case for both the moral duty we have to protect lions (as well as other threatened "big cats," tigers among them) and the economic sense such protection would make. And when one takes into account the fact that big cats are at the very top of the food chain-and that their elimination would wreak havoc on all species below them, causing a complete ecosystem collapse-the need takes on a supreme urgency.