This episode explores the nature of the greenhouse effect (discovered by Joseph Fourier and Svante Arrhenius), and the evidence demonstrating the existence of global warming from humanity's influence. Tyson begins by describing the long-term history of the planet Venus; based on readings from the Venera series of probes to the planet, the planet had once had an ocean and an atmosphere, but due to the release of carbon dioxide from volcanic eruptions, the runaway greenhouse effect on Venus caused the surface temperatures to increase and boiled away the oceans. Tyson then notes the delicate nature of the amount of carbon dioxide in the atmosphere can influence Earth's climate due to the greenhouse effect, and that levels of carbon dioxide have been increasing since the start of the 20th century. Evidence has shown this to be from mankind's consumption of oil, coal, and gas instead of from volcanic eruptions due to the isotopic signature of the carbon dioxide. The increase in carbon dioxide has led to an increase in temperatures, in turn leading to positive feedback loops of the melting polar ice caps and dethawing of the permafrost to increase carbon dioxide levels. Tyson then notes that humans have discovered means of harvesting solar power, such as Augustin Mouchot's solar-driven motor in the 19th century, and Frank Shuman's solar-based steam generator in the 1910's. Tyson points out that in both cases, the economics and ease of using cheap coal and oil caused these inventions to be overlooked at the time. Today, solar and wind-power systems would be able to collect enough solar energy from the sun easily. Tyson then compares the motivation for switching to these cleaner forms of energy to the efforts of the Space race and emphasizes that it is not too late for humanity to correct its course.

They are the most powerful objects in the universe. Nothing, not even light, can escape the gravitational pull of a black hole. Astronomers now think there are billions of them out in the cosmos, swallowing up planets, even entire stars in violent feeding frenzies. New theoretical research into the twisted reality of black holes suggests that three-dimensional space could be an illusion. That reality actually takes place on a two-dimensional hologram at the edge of the universe.

Today, we know black holes exist, and now scientists are trying to confirm that other holes lurk in hyperspace. Our infinite cosmos could contain a variety of "holes" such as black, white, "mini" and wormholes. White holes are the reverse of black holes; instead of matter being sucked into it, matter is ejected out. Wormholes are gateways in the fabric of space and time. They are included in Einstein's field equations as possibilities for their existence. Neither white holes nor wormholes have ever been found. Learn about new discoveries including, colliding binary black holes, intermediate black holes and manufacturing mini black holes.

The Universe as we know it is condemned to death. Space, matter and even time will one day cease to exist and there's nothing we can do about it. Harsh realities are revealed about the future of our Universe; it may collapse and burn or it might be gripped by a galactic ice age. Either of these scenarios might be a long way off. However, our Universe could suddenly be destroyed by a "random quantum fluctuation", a bubble of destruction that can obliterate the entire cosmos in the blink of an eye. No matter how it ends, life in our Universe is doomed.

As man moves to colonize the cosmos, the realities of sexual relationships and reproduction need to be addressed. Probe the physiological, psychological and cultural challenges of sex in space.

When mankind eventually leaves the cradle of Earth and ventures forth into the uncharted territories of the cosmos, where, and what form, will our new homes take?