Alex Gibney explores the charged issue of pedophilia in the Catholic Church, following a trail from the first known protest against clerical sexual abuse in the United States and all the way to the Vatican. The title is derived from the Latin phrase "mea maxima culpa". It is taken from the Confiteor that is part of the Roman Catholic Mass. It translates into English as "My most grievous fault" The film examines the abuse of power in the Catholic Church system through the story of four deaf men who set out to expose the priest who abused them during the mid-1960s. Each of the men brought forth the first known case of public protest against clerical sex abuse, which later lead to the sex scandal case known as the Lawrence Murphy case. Through their case the film follows a cover-up that winds its way from the row houses of Milwaukee, Wisconsin, through Ireland's churches, all the way to the highest office of the Vatican.