In the final part, Professor Al-Khalili uncovers tales of success and heartache in the story of chemists' battle to control and combine the elements, and build our modern world. He reveals the dramatic breakthroughs which harnessed their might to release almost unimaginable power, and he journeys to the centre of modern day alchemy, where scientists are attempting to command the extreme forces of nature and create brand new elements.

In this series, David Pogue explores the fantastic chemistry behind the everyday and sets out on a worldwide quest to find the key molecules and chemical reactions that have paved the way for human civilization, life, and even the universe as we know it.
In the first episode, glass so strong you can jump on it, rubber so tough it protects a clay pot dropped from 50 feet, endless varieties of plastic. Scientists and engineers have created virtually indestructible versions of common materials by manipulating the chains of interlocking atoms that give them strength—but have they made them too tough?

In this episode, Michael demonstrates how our society is built on our search to find the answer to what makes up everything in the material world. This is a story that moves from the secret labs of the alchemists and their search for gold by the stone of the philosophers to the creation of the world's first synthetic dye - Purple - and onto the invention of the transistor. This quest may seem abstract and highly theoretical. Yet it has delivered the greatest impact on humanity. By trying to answer this question, scientists have created theories from elements to atoms, and the strange concepts of quantum physics that underpin our modern, technological world.

The simple act of making an apple pie is extrapolated into the atoms and subatomic particles (electrons, protons, and neutrons) necessary. Many of the ingredients necessary are formed of chemical elements formed in the life and deaths of stars (such as our own Sun), resulting in massive red giants and supernovae or collapsing into white dwarfs, neutron stars, pulsars, and even black holes. These produce all sorts of phenomena, such as radioactivity, cosmic rays, and even the curving of spacetime by gravity. Cosmos Update mentions the supernova SN 1987A and neutrino astronomy.

To survive, animals need somewhere to live, a place that provides the necessities of life, shelter from the elements and a refuge from enemies. Good homes are rare and competition can be intense – finding a home is one thing, but defending it is quite another.

Without the chemistry of photosynthesis, ozone, and a molecule called Rubisco, none of us would be here. So how did we get so lucky? To find out, host David Pogue investigates the surprising molecules that allowed life on Earth to begin, and ultimately thrive. Along the way, he finds out what we’re all made of—literally.