A third of the population regularly struggle with our sleep, which rose to one in two during the pandemic - the highest it's ever been. However, as more and more people seek help, an explosion in sleep science is enabling the study of sleep in ways not possible before. What's more, recent breakthroughs are uncovering what's happening in our brains and bodies while we're asleep, getting us closer than ever to understanding the importance of sleep for our health. Michael Mosley shows why cutting our sleep short can be linked to a host of illnesses, including serious diseases like Alzheimer's.
Revealing the very latest science breakthroughs and packed with personal anecdotes, this programme is a useful guide to anyone looking for tips and insights on how to get the benefits from learning how to sleep well.

Follow three women at risk of developing Alzheimer’s and join a groundbreaking study to try to prevent the disease, while sharing their ups and downs, anxiously watching for symptoms, and hoping they can make a difference. Barb, Sigrid, and Karen all had mothers with Alzheimer’s and witnessed first hand the devastation wrought by the disease, not only on the mind and body, but on patients’ families.

Chris has always worked to keep his body healthy; now it’s time to start looking after his brain. Neurologist Dr. Sharon Sha challenges him to go off-grid into the wilderness without a GPS or map. Teaming up with his buddy, First Nations artist Otis Hope Carey, Chris will need to tune into nature to navigate through Otis’ remote ancestral homeland. The hike stirs up Chris’s most precious memories.

Join investigators as they untangle the cause of Alzheimer’s and race to develop a cure. Alzheimer’s disease strikes at the core of what makes us human: our capacity to think, to love, and to remember. The disease ravages the minds of over 40 million victims worldwide, and it is one of the greatest medical mysteries of our time. Join investigators as they gather clues and attempt to reconstruct the molecular chain of events that ultimately leads to dementia". Follow key researchers in the field who have helped to develop the leading theories of the disease. Along the way, meet individuals from all walks of life who will reveal what it’s like to struggle with Alzheimer’s. Among them, members of a unique Colombian family who have learned that their genetic predisposition all but guarantees early onset Alzheimer’s. Yet there may be hope. Join these courageous patients participating in clinical trials, and then go behind the scenes of the major drug trials to see how researchers target and test therapies that may slow and even prevent Alzheimer’s

This episode explores what can give brains a boost. In America, Angela tries out a new treatment that's proven to help memory and concentration. In Japan, a remarkable 100-year-old reveals the colourful foods that keep minds more active. Plus Chris discovers the best exercise we can do for our brains. At the cutting-edge of science, discover how injections of young people's blood may help beat dementia.

From the detection of gravitational waves generated in space over a billion years ago, to discoveries in genetics here on Earth, we've collected the most compelling science breakthroughs and advances of 2016. Thanks to magnificent, hard-working scientists and researchers around the world, science keeps marching ever forward. And this year saw some discoveries that are absolutely brimming with the promise of greater discoveries, breakthroughs and quality of life in the future.