A huge social experiment is underway. Fifty-five million Americans say they currently use cannabis, and that number is expected to grow as voters push for legalization in more and more states. The film investigates the story of cannabis from the criminalization that has disproportionately harmed communities of color to the latest medical understanding of the plant.
What risks does cannabis pose to the developing brain? How much do we know about its potential medical benefits? As cannabis becomes socially accepted, scientists are exploring its long-term health consequences.

At an extraordinary moment in the history of one of the world’s oldest and most controversial drugs, Dr Javid Abdelmoneim investigates the very latest medical and scientific research into the effects of cannabis on the brain and the body, to find out whether it will help or harm patients.
Javid meets the young epilepsy patient responsible for changing the law around medicinal cannabis in the UK and sees the remarkable effects it has on his condition. He visits a medicinal cannabis farm in Denmark to learn how a company known for growing the recreational drug are now producing medicinal cannabis to be exported all over Europe. He travels to Israel, to find out why they have been using cannabis as a medicine for over 20 years and meets the scientists studying the safety and effectiveness of cannabis in treating pain. And he meets the so-called godfather of cannabis, who at 88 years old is still an active research scientist and considered the world’s leading cannabis expert.

This documentary seeks to be the ultimate Odyssey of exploration into Cannabis and its uses starting from the formation of the Endocannabinoid system in the simple sea squirt, through to its early uses, the plant's various medical benefits and landing at the modern legalization movements across the Globe. Where the billions generated in tax could be re-invested back into hospitals, roads, fire departments, scientific research, community projects and the list goes on.

The documentary explores the controversial use of marijuana and the evolution of mainstream society. From a dangerous narcotic, listed as a Schedule 1 Drug substance since the 1970s, to the rush to decriminalize it today. What has changed and why? What will the cannabis industry look like in five years? Will it retain its integrity as a homegrown industry or be co-opted by Big Business? Experts, growers, celebrities and politicians weigh in on the future of Cannabusiness.