Quinto sets out to discover whether aliens exist and what evidence we have to prove it. He meets with several who say they have encountered extra-terrestrial life–a man who has been abducted by aliens several times since childhood; a man who claims to have extracted an alien implant; and a woman who shows Zachary what it feels like to be abducted into a spacecraft.
Zachary also meets with the world's leading scientists at SETI in Green Banks, West Virginia. There, utilizing the world's largest telescope, they show him the methods they employ to communicate with potential other-worldly visitors and what this research has taught them about a mysterious radio signal they picked up 3 billion light years away.

Huge asteroids have smashed into the earth, and turned it into an enveloped fire, uninhabitable to almost all life on the surface. The world will get hit again. It's just a matter of when. So, what should we do as a species? Should we just, like the dinosaurs, look up and die? The reasons the dinosaurs are extinct is they didn't have a space program. We do. We have the capability to perhaps escape the Earth.
Astronaut Chris Hadfield believes the only chance for human survival is to escape from Earth and build a space colony, but there are real barriers.

This is our home, the earth it's, it's the only place we've got. It is one strange rock because it's ours and we are here and we don't know if any other place in the universe, yet, that can support life. We're very lucky to have it as our home.
Astronauts including the legendary Peggy Whitson, who spent 665 days in space, speak about how their concepts of home have changed since their experience.

Can we find a way to distribute power so that everyone has their say? A U.S. president explains the challenges of making decisions that affect hundreds of millions of lives, and Freeman learns about an African woman who has created a society without men. He explores how the rise of the internet may fundamentally change how democracy works.

Where is everyone? We have been listening for messages from outer space for more than half a century, and so far... silence, why? Are we truly alone in the universe? Or is everyone else acting like us and just doing a lot of listening? Maybe we need to be louder. Maybe we need to send more messages out there. But how do you write a letter to an extraterrestrial whose language and culture and biology and mind we have no concept of? And what do you say?
Given all of the unknowns about what they might behave, should we say anything at all?

Since the original series went on the air in 1966, the Star Trek franchise has had a history of ups and downs in the toy business - from AMT's faithful scale model kit of the USS Enterprise to Remco's obscure tie-in merchandise, to Mego's best–selling action figure line. Following Mego's bankruptcy in 1983 and a string of flops by Ertl and Galoob, Playmates Toys picked up the toy license in the late 1980s and sparked a resurgence in the franchise's toy sales.
From the mid-2000s onwards, companies such as Art Asylum and McFarlane Toys continue to keep the Star Trek toy franchise alive.