In the second stop in his exploration of the wonders of the universe, Professor Brian Cox goes in search of humanity's very essence to answer the biggest questions of all: what are we? And where do we come from? This film is the story of matter - the stuff of which we are all made. Brian reveals how our origins are entwined with the life cycle of the stars. But he begins his journey here on Earth. In Nepal, he observes a Hindu cremation. Hindu philosophy is based on an eternal cycle of creation and destruction, where the physical elements of the body are recycled on to the next stage. Brian draws a parallel with the life cycle of the stars that led to our own creation. Next, he explains how the Earth's resources have been recycled through the ages. How every atom that makes up everything we see, was at some time a part of something else. Our world is made up of just 92 elements, and these same 92 elements are found throughout the entire universe. We are part of the universe because we are made of the same stuff as the universe.

Space colonization is no longer the fodder of science fiction, it is becoming a reality. Examine the efforts underway to establish a human colony on Mars, including how they plan to grow food, recycle wastewater and introduce greenhouse gases to revive the red planet and make it more habitable for humans. Cutting-edge computer graphics are used to bring the universe down to earth to show what life would be like on Mars, and to imagine what kind of life forms might evolve in alien atmospheres.

Across the world, rising demands for food, water and materials have pushed resources to the limit. Many parts of the world have major challenges over fresh water. A lot of soils have a lot of residual pesticides and herbicides. At the same time waste is piling higher. All this demands a new wave of innovation. The challenge is to make more of the things we need without the environmental cost.