Political humorist and author Bill Maher travels around the globe interviewing people about God and religion. Known for his analytical skills, wit and commitment to never pulling a punch, Maher brings his characteristic honesty to an unusual spiritual journey.
Muslims, Jews and Christians of many kinds pass before his jaundiced eye. He goes to a Creationist Museum in Kentucky, which shows that dinosaurs and people lived at the same time 5000 years ago. Maher speaks to a rabbi in league with Holocaust deniers. He talks to a Muslim musician who preaches hatred of Jews. Maher finds the unlikeliest of believers and, in a certain Vatican priest, he even finds an unlikely skeptic.

After the success of Florence and the Uffizi, a new film production by Sky 3D and the Vatican Television Centre, taking you on a journey through the four Papal Basilicas in Rome and their treasures: St. Peter’s (one of the 25 destinations most visited by travellers from all over the world), St. John in the Lateran, St. Mary Major and St. Paul Outside the Walls. Four majestic buildings – each with a precious papal altar, each a treasure trove of timeless works of art and a destination for millions of travellers and pilgrims over the centuries – play the leading role in a new film tour that has been recognized as a work of cultural interest by the film board of the Ministry of Culture, Heritage and Tourism.

Alex Gibney explores the charged issue of pedophilia in the Catholic Church, following a trail from the first known protest against clerical sexual abuse in the United States and all the way to the Vatican. The title is derived from the Latin phrase "mea maxima culpa". It is taken from the Confiteor that is part of the Roman Catholic Mass. It translates into English as "My most grievous fault" The film examines the abuse of power in the Catholic Church system through the story of four deaf men who set out to expose the priest who abused them during the mid-1960s. Each of the men brought forth the first known case of public protest against clerical sex abuse, which later lead to the sex scandal case known as the Lawrence Murphy case. Through their case the film follows a cover-up that winds its way from the row houses of Milwaukee, Wisconsin, through Ireland's churches, all the way to the highest office of the Vatican.

In the fourth episode, Morgan Freeman examines how different faiths see the creation of the world, taking him on a journey to the Vatican, Cairo and the jungles of Guatemala.